學術研究 • ACADEMIC RESEARCH 54 澳大新語 • 2024 UMAGAZINE 30 high-voltage-tolerant switches also play a crucial role during nuclear excitation as they protect the receiver and reduce noise during acquisition, thereby ensuring optimal signal quality and system performance. In the medical field, 19F tracking is a hallmark application of multi-nuclei MRI. To evaluate the performance of this new system, we used perfluorocarbon (PFC) as an MRI contrast agent and injected it into the ex vivo porcine sample to obtain 1H/19F images. The 1H image details the structure of the porcine sample (muscle and fat), while the 19F image shows the location of the PFC. We found that combining these images allows precise tracking and analysis of specific chemical substances within the sample. The application of this technology in a 「學術研究」為投稿欄目,內容僅代表作者個人意見。 Academic Research is a contribution column. The views expressed are solely those of the author(s). 范姝豪在2024年獲澳門大學博士學位,2016年獲東北林業大學學士學位、2017年獲香港科技大學碩士學位,曾在2024年 於哈佛大學當訪問生,研究重點是便攜式NMR/MRI平台與定製集成電路,成果曾在IEEE國際固態電路會議、《IEEE固態電 路期刊》、《IEEE電路與系統期刊-I》和國際微全分析系統會議等會議和期刊上發表。 Fan Shuhao obtained her PhD from the University of Macau in 2024. She earned her BSc degree from Northeast Forestry University in 2016, and her MSc degree from the Hong Kong University of Science and Technology in 2017. She was also a visiting student at Harvard University in 2024. Her research interests include portable NMR/MRI platforms with customised integrated circuits, and her work has been featured in conferences and journals such as the IEEE International Solid-State Circuits Conference, IEEE Journal of Solid-State Circuits, IEEE Transactions on Circuits and Systems I: Regular Papers, and the International Conference on Miniaturized Systems for Chemistry and Life Sciences. 李家明於2019年起在澳門大學微電子研究院擔任助理教授,分別於2012年和2016年澳門大學獲學士學位和博士學位,研 究興趣包括精密模擬集成電路、傳感器與模擬前端接口,以及高解析度的便攜式NMR/MRI平台。 Lei Ka Meng has been an assistant professor in the Institute of Microelectronics at the University of Macau (UM) since 2019. He received his BSc and PhD degrees from UM in 2012 and 2016, respectively. His research interests include precision analogue integrated circuits, sensors and analogue front-end interfaces, and high-resolution portable NMR/MRI platforms. miniaturised multi-nuclei NMR/MRI system marks a milestone in our research and development efforts. Advancing Personalised Medicine We believe that this compact, miniaturised multi-nuclei NMR/MRI system will drive advancements in personalised medicine. By enabling in-depth molecular analysis of body tissues, the system has the potential to revolutionise early disease detection, treatment strategies, and disease management. As our team continues to make strides in CMOS integrated circuit technology, we are setting the stage for a future where this sophisticated imaging technology becomes a standard tool in healthcare, offering medical professionals more powerful diagnostic capabilities than ever before. 以MRI技術在注入了全氟化碳的豬肉樣本中追蹤氫-1和氟-19,從而區分樣本中的肌肉(T1:191.2毫秒)和脂肪(T1:82.9毫秒)。 MRI tracking of 1H and 19F in the porcine sample injected with PFC, which helps differentiate between muscle (T1: 191.2 ms) and fat (T1: 82.9 ms) in the sample
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