COVER STORY•封面專題 2020 UMAGAZINE 22•澳大新語 20 Androgens play an essential role in the growth of prostate cancer cells, but the exact mechanism remains unclear. Prof Edwin Cheung Chong Wing’s team, in the Faculty of Health Sciences, was among the first to show how the androgen receptor (AR) regulates gene expression in the 3D structure of genome to mediate the development of prostate cancer. This important finding could potentially help prostate cancer treatment. 雄激素在前列腺癌細胞的生長中發揮重要作用，但其運作機制仍然充滿未知。 健康科學學院張仲榮教授的團隊研究首創性發現雄激素受體如何在基因組的三維 結構下調控基因表達，以介導前列腺癌的發展，其發現可望有助治療前列腺癌。 治療前列腺癌的新機制 A New Mechanism for Prostate Cancer Treatment 文/盛惠怡‧圖/編輯部，部分由受訪者提供 Chinese & English Text / Debby Seng ‧ Photo / Editorial Board with some provided by the interviewee 雄激素受體介導的前列腺癌細胞基因表達的遠距離調控 Long-range regulation of gene expression mediated by AR in prostate cancer cells
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